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目的探讨白内障超声乳化吸除联合人工晶状体植入手术对糖尿病患者泪液的影响。方法选择30例单纯性老年性白内障患者和30例患有糖尿病的白内障患者,分别为对照组和糖尿病组。在术后4个时间点7 d、15 d、1个月和3个月进行干眼症状评分,光学相干断层扫描(OCT)分析泪河高度,泪膜破裂时间(break-up time,BUT)和SchirmnerⅠ结果测定,对2组上述指标进行分析。结果术后7 d、15 d及1个月糖尿病组干眼症状评分分数较高(P<0.05);术后3个月对照组较糖尿病组干眼症症状评分差异无统计学意义(P>0.05)。术后7 d、15 d、1个月及3个月对照组较糖尿病组泪河线高度数值高,BUT时间长,差异有统计学意义(P<0.05或<0.01)。术后15 d、1个月及3个月糖尿病组SchirmnerⅠ长度较对照组明显减少,差异有统计学意义(P<0.01)。结论糖尿病组较对照组白内障超声乳化吸出联合人工晶体植入术后干眼症状重,且持续时间更长。
Objective To investigate the effect of phacoemulsification combined with intraocular lens implantation on the tear of diabetic patients. Methods Thirty patients with simple senile cataract and 30 patients with cataract with diabetes were selected as the control group and the diabetic group. Dry eye symptoms were scored at 7 days, 15 days, 1 month and 3 months after operation at 4 time points. The tear height, tear-break time (BUT) And Schirmner Ⅰ results were measured, two groups of the above indicators were analyzed. Results The score of dry eye symptom in diabetic group was significantly higher at 7 d, 15 d and 1 month after operation (P <0.05), and there was no significant difference in the symptoms of dry eye between diabetic group and control group at 3 months after operation (P> 0.05). At 7 d, 15 d, 1 month and 3 months after operation, the height of the tear river in the diabetic group was higher than that in the diabetic group, and the duration of BUT was longer (P <0.05 or <0.01). The Schirmner Ⅰ length at 15 d, 1 month and 3 months after operation in diabetic group was significantly lower than that in control group, with significant difference (P <0.01). Conclusion Compared with the control group, the diabetes mellitus patients with dry eye symptoms after cataract phacoemulsification combined with intraocular lens implantation have longer duration.