论文部分内容阅读
本文将急性非淋巴细胞白血病初诊骨髓片255份及治疗后髓片中Auer小体进行回顾性观察，结果表明Auer小体在急性髓细胞白血病中有高度特异性，Auer小体多为棒状、分布于近核处，其次为柴捆状、弧形、针尖状等不同形态。Auer小体在M3型白血病细胞中检出率及Auer小体阳性细胞百分率均显著高于其他类型（P＜0．01），其次为M2b型。柴捆状Auer小体的发现在M3型中具有特征性变化。全反式维甲酸治疗获得CR的8例骨髓片中，中、晚幼粒细胞，甚至成熟粒细胞中可见1～5条Auer小体，证实经诱导分化治疗后白血病细胞在体内能分化为成熟阶段。
In this paper, retrospective observations were performed on 255 newly diagnosed bone marrow pieces of acute non-lymphocytic leukemia and Auer bodies on treated medullary slices. The results showed that Auer bodies were highly specific in acute myeloid leukemia, and Auer bodies were mostly rod-shaped and distributed. Near the nucleus, followed by different forms of firewood, arc, needlepoint and so on. The detection rate of Auer bodies and the percentage of positive Auer bodies in M3 leukemia cells were significantly higher than those of other types (P<0.01), followed by M2b type. The discovery of wood bundled Auer bodies has a characteristic change in the M3 type. All-trans retinoic acid treatment of 8 cases of CR obtained bone marrow tablets, medium and late myeloid cells, and even mature granulocytes visible 1 to 5 Auer bodies, confirmed that after induction differentiation treatment of leukemia cells can differentiate into mature in vivo stage.