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采用结扎冠状动脉方法,造成犬急性心肌缺血模型,观察精制血府胶囊抗心肌缺血的作用。结果表明,该药可明显减轻结扎冠状动脉造成的犬心肌缺血程度、减小缺血范围、缩小心肌梗死面积,显著降低犬结扎冠状动脉后血清心肌酶CK活性,表明该药有较好的抗心肌缺血损伤的作用。
The method of ligation of coronary arteries was used to induce acute myocardial ischemia in dogs and the effect of purified Xuefu capsules on myocardial ischemia was observed. The results showed that the drug can significantly reduce canine myocardial ischemia induced by ligation of coronary arteries, reduce the ischemic range, reduce the myocardial infarct size, significantly reduce the serum myocardial enzyme CK activity after canine ligation of coronary arteries, indicating that the drug has better Anti-myocardial ischemic injury.