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益气健脾口服液合并化疗治疗胃癌61例,与对照组40例对比观察治疗。其结果显示因化疗引起的恶心呕吐发生率,治疗组比对照组明显减少(P<0.01)。治疗组的化疗完成率为95%,对照组为78%(P<0.01);白细胞和血小板下降率,两组相比,P均<0.01。说明益气健脾口服液有较好的减轻甚则解除单纯化学药物治疗所引起的胃肠道及血像的毒、副反应。对治疗满1年以上的治疗组60例患者进行了随访,其中1、3、5年生存率分别为98.36%、82.69%和60.00%。治疗组中Ⅲ期患者5年生存率为57.14%。动物实验显示,益气健脾口服液对小鼠B16肺转移抑制率为92.2%和83.7%,与对照组比较P<0.01。益气健脾口服液还可以提高动物对化疗药物的耐受量。
Yiqi Jianpi Oral Liquid combined with chemotherapy for 61 cases of gastric cancer, compared with 40 cases in the control group to observe treatment. The results showed that the incidence of nausea and vomiting due to chemotherapy was significantly lower in the treatment group than in the control group (P<0.01). The completion rate of chemotherapy in the treatment group was 95%, 78% in the control group (P<0.01), and the decrease rate of white blood cells and platelets, compared with the two groups, P<0.01. The results showed that the Qiqi Jianpi oral solution was better relieved and even relieved the toxic and side effects of the gastrointestinal tract and blood caused by simple chemical drug treatment. 60 patients with treatment for more than one year were followed up. The 1-, 3-, and 5-year survival rates were 98.36%, 82.69%, and 60.00%, respectively. The 5-year survival rate of stage III patients in the treatment group was 57.14%. Animal experiments showed that the inhibitory rate of lung metastasis in mice with B16 was 92.2% and 83.7%, respectively, compared with the control group (P<0.01). Yiqi Jianpi Oral Liquid can also increase the tolerance of animals to chemotherapeutic drugs.