目的对1例唇腺导管结石病例进行临床分析并文献回顾。方法患者局麻下行手术切除治疗,根据病理组织学特点最终确诊。结果本文病例为下唇粘膜缓慢长大包块,色白,偶有胀痛,实验室检查无明显异常,病理确诊为下唇腺导管内结石伴感染。结论小涎腺结石临床无特异性,诊断较为困难,容易误诊,手术切除合并病理是确诊的主要手段。 Objective To analyze the clinical data and literature review of one case of labial calculus. Methods Patients underwent surgical resection of local anesthesia, the final diagnosis based on histopathological features. Results In this case, the lower lip mucosa slowly grew up mass, color white, occasional pain, laboratory tests showed no abnormalities, the pathology was diagnosed as lower labial duct stones with infection. Conclusions Small salivary gland calculi are non-specific clinical diagnosis is more difficult, easy to misdiagnosis, surgical excision combined with pathology is the main means of diagnosis.