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[目的]分析延边农村地区朝鲜族和汉族人群空腹血糖受损与多种代谢异常的相关性.[方法]在延边农村地区随机选择2个自然村,采用整群抽样的方法抽取3 217人作为研究对象,年龄在30~70岁之间.通过问卷的方式收集研究对象的一般情况,内容包括调查对象的性别、年龄、民族、职业等一般情况、饮食、吸烟、饮酒、疾病家族史及本人既往史.通过体格检查的方式,测定体质量指数(BMI)、腰围(WC)、血压(BP)、空腹血糖(FBG)、三酰甘油(TG)、高密度脂蛋白-胆固醇(HDL-C)、血尿酸(UA)、谷氨酰转移酶(GGT)及胰岛素(FINS)等代谢指标.按照GGT,UA及胰岛素抵抗指数(HOMA-IR)、胰岛β细胞分泌指数(HOMA-β)、胰岛素敏感性指数(ISI)水平四分位数把研究对象分为4组后进行分析.[结果]整体型肥胖、腹型肥胖、高血压、高三酰甘油血症、低HDL-C血症组的空腹血糖升高(IFG)患病率显著高于血糖正常组(P<0.05),且随着BMI水平的增高,IFG的检出率有升高的趋势(P<0.001).GGT四分位点的IFG检出率分别为11.2%,13.1%,17.3%,18.0%,UA分别为11.2%,15.1%,13.3%,19.5%,HOMA-IR分别为7.2%,11.3%,10.6%,33.2%,HOMA-β分别为24.7%,17.8%,13.5%,4.9%,ISI分别为33.2%,10.6%,11.3%,7.2%,升高或降低趋势均有统计学意义(P<0.001).[结论]不同代谢异常组IFG检出率显著高于代谢正常组,GGT,UA,HOMA-IR,HOAM-β及ISI对IFG患病危险的影响具有剂量反应关系.
[Objective] To analyze the correlation between impaired fasting glucose and various metabolic abnormalities in Korean and Han nationality population in Yanbian rural areas. [Method] Two villages were randomly selected in rural areas of Yanbian. A total of 3 217 people were selected as samples by cluster sampling Subjects, aged 30 to 70. The general situation of the subjects was collected by questionnaire, including the general conditions of the subjects such as sex, age, ethnicity and occupation, diet, smoking, drinking, family history of disease and my past The body mass index (BMI), waist circumference (WC), blood pressure (BP), fasting blood glucose (FBG), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C) , UA, GGT and FINS were detected by ELISA.GGT, UA, HOMA-IR, HOMA-β, Sensitivity index (ISI) quartiles divided the subjects into four groups for analysis. [Results] The overall obesity, abdominal obesity, hypertension, hypertriglyceridemia, low HDL-C group The prevalence of elevated fasting glucose (IFG) was significantly higher than that of blood glucose (P <0.05), and the detection rate of IFG increased with the increase of BMI (P <0.001) .The IFG detection rates of GGT quadrant were 11.2%, 13.1% and 17.3 HOMA-β were 7.2%, 11.3%, 10.6%, 33.2%, and HOMA-β were 24.7%, 17.8% and 13.5%, respectively, and UA were 11.2%, 15.1%, 13.3% and 19.5% , 4.9% and ISI were 33.2%, 10.6%, 11.3% and 7.2%, respectively. The detection rate of IFG in different metabolic abnormalities group was significantly higher than that of metabolic The normal group, GGT, UA, HOMA-IR, HOAM-β and ISI had a dose-response relationship with the risk of IFG.