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病毒引起的肺吞噬细胞防御能力受到抑制是因为肺泡巨噬细胞使细菌体内的各种过程发生缺陷所致。为确定细胞内缺陷是否是由于吞噬体—溶酶体不能融合,作者用亚致死量副流感Ⅰ型(仙台)病毒,经气溶胶吸入
The virus-induced lung phagocyte defense is inhibited because alveolar macrophages cause defects in various processes in the bacterium. To determine whether intracellular defects are due to inability of the phagosome-lysosomes to fuse, the authors used aerosol inhalation of a sublethal parainfluenza type 1 (Sendai) virus