皮肤局部用药种类繁多,一般要求药物在皮肤表面或透入皮肤后发挥局部作用,不产生全身效应,对某些吸收后会引起不良反应的药物应注意避免皮肤吸收。然而,近年来有的药物经透皮吸收后产生的全身作用却引起了国内外学者的极大兴趣。例如,硝酸甘油口服后胃肠道易破坏,舌下给药奏 Topical application of a wide range of skin, the general requirements of the skin surface or penetrate the skin to play a local role, does not produce systemic effects, some of the absorption will cause adverse reactions to the drug should be taken to avoid skin absorption. However, in recent years, the systemic effects of some drugs after transdermal absorption have aroused great interest of scholars at home and abroad. For example, nitroglycerin after oral administration of gastrointestinal tract easily destroyed, sublingual administration played