以杯[4]芳烃-1,3-二溴乙氧基衍生物1为合成平台,在K2CO3/MeCN体系中分别与乙醇胺、L-亮氨醇、2-巯基苯并咪唑、巯基乙酸乙酯反应,以49%～76%的产率合成了4种新型含氮、硫杂官能团的杯[4]芳烃衍生物2,4,5和6.化合物2进一步与异硫氰酸苯酯反应,以84%的产率得到了新型树枝状杯[4]芳烃氮、硫杂衍生物3.新化合物的结构与构象经元素分析、质谱、核磁共振谱等表征证实. The synthesis of calix [4] arene-1,3-dibromoethoxy derivative 1 was carried out on a K 2 CO 3 / MeCN system with ethanolamine, L-leucine, 2-mercaptobenzimidazole and ethyl thioglycolate , Four new calix [4] arene derivatives 2,4,5 and 6 were synthesized in yields of 49% ~ 76% .Compound 2 was further reacted with phenylisothiocyanate, The new dendritic calix [4] arene nitrogen and thio derivatives were obtained in 84% yield. The structures and conformations of the new compounds were confirmed by elemental analysis, mass spectrometry and nuclear magnetic resonance spectroscopy.