应用药物使输卵管堵塞达到绝育目的在国外已有100余年历史,但至今效果还不够满意。国内近十年来各单位进行了研究,成功率逐渐上升。复方苯酚糊剂(简称“三合一”),在上海地区临床试用3653例,最长已超过七年,远期疗效稳定在99.29％,但近期有发热、腹痛、腰酸等副反应,为此进行了一些药理试验,对造成副反应的原因进行探讨,并改进了原处方。 The application of drugs to tubal blockage achieve sterilization purposes in foreign countries have more than 100 years of history, but so far the results are not satisfactory. In the past ten years, all units conducted research and the success rate has been gradually rising. Compound phenol paste (referred to as “three in one”), clinical trials in Shanghai 3653 cases, the longest has more than seven years, the long-term efficacy was stable at 99.29%, but recent fever, abdominal pain, backache and other side effects, A number of pharmacological tests were carried out to investigate the causes of side effects and to improve the original prescription.