There is evidence that gonadal hormones may affect the perception of painful stimulation, although the underlying mechanisms remain unclear.This investigati
The delayed rectifier potassium current (IK) is a major outward current responsible for ventricular muscle action potential repolarization.In most species,I
ThermoTRP channels are expressed in sensory neurons where they detect a variety of physical and chemical stimuli including temperature, ionic strength, memb
Ion channels are involved in the migration of tumor cells that is required for their invasion and metastasis.In this present study, we describe the role of
Stretch-activated chloride currents (IC1,sA) have been considered to be a component of volume-activated chloride currents (ICl.vol) for some time.This is du
Membrane phosphatidylinostol 4,5-bisphosphates (PtdIns(4,5)P2, PIP2) is fundamentally important for maintaining function of a large number of ion channels a