过去二十年胃腺癌在发生部位、组织学类型、临床表现、手术态度等方面饭示很大变化。近端部位胃癌占全部胃癌的比例有上升趋势，同时食管远端癌发病率也迅速增加，而且临床特点和近端胃癌相近。如男性为主，弥漫性、分化下良的组织学类型的癌的百分率逐渐增高，临床浅表胃癌更常见。 Gastric adenocarcinoma has undergone major changes in the sites, histological types, clinical manifestations, and surgical attitudes during the past two decades. The proportion of gastric cancer in the proximal part of the stomach has increased, and the incidence of cancer in the distal esophagus has also rapidly increased. The clinical features are similar to those in the proximal gastric cancer. If men are predominant, the percentage of histologically typed cancers that are diffuse and differentiated gradually increases, and clinically superficial gastric cancers are more common.