【摘 要】
:
Objective:To study the effect of tumor infiltrating lymphocytes at cancer nest on local control of rectal cancer after preoperative radiotherapy.Methods:From Ja
【机 构】
:
Department of Radiotherapy,Peking University School of Oncology,Beijing Cancer Hospital & Institute,
论文部分内容阅读
Objective:To study the effect of tumor infiltrating lymphocytes at cancer nest on local control of rectal cancer after preoperative radiotherapy.Methods:From Jan.1999 to Oct.2007,a total of 107 patients with rectal cancer were reviewed.They were treated by preoperative radiotherapy,30 Gy/10 fractions/12 days.Two weeks later,the patient underwent a surgical operation.Their pathological samples were kept in our hospital before and after radiotherapy.Lymphocyte infiltration(LI)degree,pathologic degradation and fibrosis degree after radiotherapy in paraffin section were evaluated under microscope.Results:After followed-up of 21 months(2-86 months),a total of 107 patients were reviewed.Univariate analysis showed that lymphocyte infiltration(LI),fibrosis and pathologic changes after radiotherapy were significant factors on local control.Logistic regression analysis showed that LI after radiotherapy was a significant effect factor on local control.Conclusion:LI,fibrosis and pathologic degradation after radiotherapy are significant for local control of rectal cancer after preoperative radiotherapy.LI after radiotherapy was a significantly prognostic index for local control of rectal cancer after preoperative radiotherapy.
其他文献
Objective:To study the serum protein fingerprint of patients with pancreatic cancer and to screen for protein molecules closely related to pancreatic cancer dur
Objective:To investigate the expressions of Beta-catenin,E-cadherin and MMP-7 and their implications in ovarian epithelial tumor.Methods:lmmunohistochemicai sta
长期大剂量左旋多巴治疗帕金森氏综合征,仅能维持3~4年的最适当的疗效,此后多再无明显疗效,副作用多,且难以处理,此时可停用左旋多巴,直至绝对需要时再开始用最小剂量治疗。
一项新的研究显示,每天练习20 min的瑜伽,就能立即刺激大脑、提升大脑功能。练习瑜伽后,不仅注意力更集中、记忆力变好,而且学习能力也大为提升。美国伊利诺大学香槟分校的研
Objective:To evaluate the rate and types of human papillomavirus(HPV)infection in cervical adenocarcinoma.Methods:We detected and identified HPV in 67 lesions u
Objective:To investigate the proliferation effect and its pathway of activin A on Ovarian epithelial cancer cells line OVCAR-3.Methods:OVCAR-3 cells were cultur
Objective:To study interpectoral nodes metastasis rate in breast cancer and its clinical significance.Methods:171 female patients undergone surgery for breast c
2001年大事喜事多,突发事件多。北京市的新闻单位在市委的领导下,在 中宣部的关心、指导下,高举邓小平理论的伟大旗帜,坚持同以江泽民同志为核 心的党中央保持高度一致,“认清形势、坚
Mr and Mrs Jones very seldom go out in the evening, but last Saturday, Mrs Jones said to her husband,
Mr and Mrs Jones very seldom go out in the evening, but l
大力推动高等职业教育的发展已经成为我国一个重要的教育方略。作为高等教育系统的一个重要类型,高等职业教育是一种以职业岗位群或某科技领域为导向的,以“能力培养为中心”并