Mercury pollution in the Three Gorges Reservoir area of P. R. China merits special attention. We investigated into the current situation in the Chongqing part of the Reservoir area, identified the pollution sources and proposed some suggestions for the remediation and prevention of mercury pollution in this area. Atmospheric mercury in Chongqing was mainly from coal bing and releases of mercury-containing products such as various types of lights and fever thermometers. Urban drainage in Chongqing and Changshou, and runoffs from the high mercury background area in the lower reaches of the Wujiang River contributed most of the mercury in the water of the Yangtze River. A majority of the blame should be laid on mercury and gold mining in the Wujiang valley. We suggested foresting sloping lands to relieve soil erosion and prevent mercury-bearing soil from running into rivers, educational activities to discourage use of mercury-containing products and improved infrastructure to collect mercury-containing wastes for reducing mercury releases, more facilities for treating wastewater and solid waste to accommodate increased requirements of discharge, and growing selected perennial plants in mercury-contaminated land to absorb the mercury in soil. We also suggested concerted operation of a dedicated water-quality monitoring system, reinforced legislation and an effective administrative mechanism to ensure lasting efforts are invested in curbing mercury releases and restoring mercury contaminated land and water in the Reservoir area.