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尼氏小体(尼氏物质或颗粒)形状、数量和分布的变化对病理学诊断和生理学研究均具有重要意义。尼氏小体的显示:方法一般采用甲苯胺蓝、硫堇、焦油紫和焦性没食子蓝等碱性染料。由于尼氏小体主要成份为核糖核酸,故用组化技术也可显示。多数方法均较繁复费时,有的需时长达12～48小时,且色呈蓝或紫而不艳。根据尼氏小体对碱性染料易染之特点,经笔者探索改进采用 Ziehl—Neelsen 石碳酸复红显示。
Changes in the shape, number, and distribution of Nissl’s bodies (nitrides or granules) are important for pathological diagnosis and physiology. Nissl body shows: the method generally used toluidine blue, thionine, tar purple and coke gallogamy and other basic dyes. Since Nissl’s body is mainly composed of ribonucleic acid, it can also be displayed by tissue engineering. Most methods are more complicated and time-consuming, and some take up to 12 to 48 hours, and the color was blue or purple without Yan. According to Nissl body of alkaline dye easily dye characteristics, by the author to explore the use of Ziehl-Neelsen carbolic acid complex red display.