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影响恶性胃溃疡内镜活检诊断率的因素有:病变部位的活检标本数、活检组织的多少、医师的经验、肿瘤的部位和形态学、活检有无辅以细胞学检查等。本文对取自溃疡边缘或底部的活检标本,比较评估其诊断阳性率和潜在危险性。病人和方法选用胃溃疡病48例,年龄24～78(平均64.8)岁。溃疡直径均>2cm,病理检查证实46例(男42,女4)为腺癌,2例为淋巴肉瘤。每例均自溃疡边缘或底部,用标准活检钳各取6个内镜活检标本。经甲醛固定和苏木精-伊红染色后进行镜检,
The factors influencing the diagnostic rate of endoscopic biopsy for malignant gastric ulcer include: the number of biopsy specimens at the lesion site, the number of biopsy tissues, the physician’s experience, the location and morphology of the tumor, and the presence or absence of cytology for biopsy. This article compares the biopsy specimens taken from the edge or bottom of the ulcer to the diagnostic positive rate and potential risk. Patients and methods used gastric ulcer in 48 cases, aged 24 to 78 (average 64.8) years old. The ulcer diameters were all >2cm. Pathological examination confirmed 46 cases (male 42, female 4) as adenocarcinoma and 2 cases as lymphosarcoma. Each case was taken from the edge or bottom of the ulcer and 6 endoscopic biopsy specimens were taken using standard biopsy forceps. Microscopy after formalin fixation and hematoxylin-eosin staining