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目的:比较2μm激光与等离子电切治疗良性前列腺增生(BPH)的疗效,系统评价2μm激光临床应用效果,为临床提供参考依据。方法:收集已发表的关于2μm激光和等离子电切治疗BPH的国内外文献,针对结果进行统计学综合分析(Meta)。终末指标采用SMD值及95%CI进行比较分析,统计学处理采用Revman5.0软件。结果:共7篇文献符合纳入标准,对2μm激光组的463例和等离子电切组的608例进行分析。Meta分析显示:1等离子电切组手术时间少于2μm激光组,差异有统计学意义(P<0.01);22μm激光组术中出血量小于等离子电切组,差异有统计学意义(P<0.01);32μm激光组术后留置尿管时间少于等离子电切组,差异有统计学意义(P<0.01);42μm激光组膀胱冲洗时间少于等离子电切组,差异有统计学意义(P<0.01);52μm激光组住院时间少于等离子电切组,差异有统计学意义(P<0.01)。结论:2μm激光具有出血少、创伤小、术后恢复快等优势,治疗BPH安全可靠。
Objective: To compare the curative effect of 2 μm laser and plasma tangential excision on benign prostatic hyperplasia (BPH), and evaluate the clinical effect of 2 μm laser to provide a reference for clinical practice. Methods: The published literature on BPH treated with 2 μm laser and plasma tangential excision was collected, and the results were statistically analyzed (Meta). The final index using SMD value and 95% CI for comparative analysis, statistical processing using Revman5.0 software. Results: A total of 7 articles met the inclusion criteria and analyzed 463 cases in the 2 μm laser group and 608 cases in the plasma tangential group. The results of Meta-analysis showed that: 1 plasma cutting operation time less than 2μm laser group, the difference was statistically significant (P <0.01); 22μm laser group bleeding less than plasma cutting group, the difference was statistically significant (P <0.01 ). The duration of indwelling catheter in 32μm laser group was shorter than that in plasma-cut group, the difference was statistically significant (P <0.01); the bladder flushing time in 42μm laser group was less than that of plasma cutting group (P < 0.01). The hospitalization time of 52μm laser group was less than that of plasma cutting group, the difference was statistically significant (P <0.01). Conclusion: 2μm laser has the advantages of less bleeding, less trauma and faster postoperative recovery, which makes BPH safe and reliable.