枸橼酸乙胺嗪(海群生)是治疗丝虫病较理想的药物。它对人的毒性很小,对微丝蚴和丝虫成虫都有很好的杀灭作用。它的缺点是,服后微丝蚴死亡会引起发热、头痛、全身疫痛等过敏反应,特别是马来丝虫病人,这些反应比较厉害。用复方阿司匹林片可使这些反应得到一定程度的减轻或缓解。海群生治疗丝虫病的剂量、疗程问题,国内曾作了大量的研究。为适应大规模防治工作的需要,其总趋势是:由小剂量长疗程转为大剂量短疗程;由一天多次服药转为一天单次服用;由一个疗程转为多个疗程。此外,班氏丝虫较马来丝虫需要剂量大和疗程多,同一种丝虫,微丝蚴密度高者較微丝蚴密度低者需要剂量大和疗程多。目前国内采用的疗法,各地还不一致,常用者有以下三种。 (一)1天1克(或1.5克)疗法这种疗法是1天单次服1克(或1.5克)。疗程计算方法又有两种:一是连服2～3天为一疗程,常用 Ethidium citrate (sea qun) is the ideal treatment for filariasis drugs. It is very toxic to humans and has a good killing effect on microfilariae and filarial adults. Its disadvantage is that the death of microfilaria after the service can cause fever, headache, systemic anaphylaxis and other allergic reactions, especially Malay filariasis patients, these reactions are more severe. With the compound aspirin tablets can make these reactions to a certain extent, reduce or alleviate. Sea group treatment filariasis dose, treatment problems, made a lot of domestic research. In order to meet the needs of large-scale prevention and control work, the general trend is: from a small dose of long courses into large doses of short courses; from one day to several times a day to take a single medication; from one course to multiple courses. In addition, Bancroftian filariasis than Malayan insects require a large dose and treatment, the same type of filariasis, microfilaria lamellae densities are higher than those with low microfilaria lavage dose and treatment. Currently used therapy, not the same throughout the country, there are three commonly used users. (A) 1 day 1 gram (or 1.5 grams) therapy This therapy is a single one-day service 1 g (or 1.5 grams). There are two calculation methods of treatment: First, even serving 2 to 3 days for a course of treatment, commonly used