Control of ion transport and fluid flow through nanofluidic devices is of primary importance for energy storage and conversion,drug delivery and a wide range of biological processes.Recent development of nanotechnology,synthesis techniques,purification technologies,and experiment have led to rapid advances in simulation and modeling studies on ion transport properties.In this review,the applications of Poisson-Nest-Plank (PNP) equations in analyzing transport properties are presented.The molecular dynamics (MD) studies of transport properties of ion and fluidic flow through nanofluidic devices are reported as well.