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目的探讨苯磺酸左旋氨氯地平片治疗高血压患者的临床效果。方法随机选取高血压患者196例,将其分为两组,每组98例。对照组给予硝苯地平缓释片治疗,观察组给予苯磺酸左旋氨氯地平片。比较治疗后两组降压效果及不良反应。结果治疗8周,总有效率对照组为83.7%(82/98),观察组为97.9%(96/98),两组总有效率比较差异有统计学意义(P<0.05)。治疗8周,观察组血压下降水平明显高于对照组(P<0.05)。不良反应发生率观察组为12.2%(12/98),对照组为30.6%(30/98),观察组不良反应发生率低于对照组(P<0.05)。结论苯磺酸左旋氨氯地平片治疗高血压临床效果明显,适合于不同年龄段的高血压患者,降压效果持久,不良反应少,安全性较高。
Objective To investigate the clinical effect of levamlodipine besylate on patients with hypertension. Methods 196 cases of hypertensive patients were randomly selected and divided into two groups, 98 cases in each group. The control group was given nifedipine sustained-release tablets and the observation group was given levamlodipine besylate tablets. Compare the antihypertensive effect and adverse reaction of two groups after treatment. Results After 8 weeks of treatment, the total effective rate was 83.7% (82/98) in the control group and 97.9% (96/98) in the observation group. The total effective rate was significantly different between the two groups (P <0.05). After 8 weeks of treatment, the decrease of blood pressure in the observation group was significantly higher than that in the control group (P <0.05). The incidence of adverse reactions in the observation group was 12.2% (12/98) in the control group and 30.6% (30/98) in the control group. The incidence of adverse reactions in the observation group was lower than that in the control group (P <0.05). Conclusion L-amlodipine besylate tablets have obvious clinical effect in the treatment of hypertension. It is suitable for patients with hypertension in different ages and has long-lasting antihypertensive effect with less adverse reactions and higher safety.