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目的:观察危重症患者血糖波动系数(GV)及炎性因子C反应蛋白(CRP)的水平,并评估其在判断预后中的价值。方法:搜集71例危重症患者入院24h内的血糖监测值及CRP水平,计算GV与CRP水平的相关性,并分析GV与危重症患者APACHEⅡ评分的关系,追踪其早期预后。结果:全部患者入院时血清CRP水平均较正常值高,且GV与CRP呈正相关(P<0.01);GV、CRP与APACHEⅡ评分均呈正相关(均P<0.01);低GV组预后明显优于高GV组(P<0.05)。结论:危重症患者GV与血清CRP均明显升高且二者间存在正相关关系,GV可作为预测危重症患者预后的独立因素,故临床治疗过程中应通过积极控制血糖波动水平改善预后。
Objective: To observe the level of glycemic index (GV) and inflammatory factor C-reactive protein (CRP) in critically ill patients and to evaluate its value in predicting the prognosis. Methods: The blood glucose monitoring and CRP levels in 71 critically ill patients admitted within 24 h were collected. The correlation between GV and CRP levels was calculated. The relationship between GV and APACHE Ⅱ scores in critically ill patients was analyzed and its early prognosis was tracked. Results: Serum CRP levels of all patients were higher than normal at admission, and there was a positive correlation between GV and CRP (P <0.01). There was a positive correlation between GV, CRP and APACHEⅡscore (all P <0.01) High GV group (P <0.05). Conclusion: GV and CRP in critically ill patients are significantly increased and there is a positive correlation between them. GV can be used as an independent predictor of prognosis in critically ill patients. Therefore, the prognosis should be improved by actively controlling the blood glucose level during the course of clinical treatment.