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报告1例多发性鲍恩病。患者女,46岁。全身散在多发丘疹、斑块伴瘙痒4年余。患者曾有砷类化合物接触史,停止接触10余年后发病。皮肤科检查:右侧肩部、双侧腕部、小腿及双足散在分布十余个大小不等圆形及不规则形暗红色丘疹、斑块,0.5 cm×0.5 cm~3.0 cm×2.5 cm,表面干燥,部分皮损表面附着厚痂皮及鳞屑,边界清楚,右侧腕部皮疹表面痂皮脱落,基底轻微糜烂、渗出,黏膜部位未见累及。皮损组织病理检查:表皮不规则增生肥厚,细胞排列紊乱,非典型增生,可见角化不良细胞及病理性核分裂象。诊断:多发性鲍恩病。
One case of multiple Bowen’s disease was reported. Female patient, 46 years old. Multiple scattered systemic papules, plaque with itching more than 4 years. Patients had exposure to arsenic compounds history, stop the contact after more than 10 years of onset. Dermatology examination: the right shoulder, bilateral wrist, calf and bipedal scattered around the size of more than 10 round and irregular dark red papules, plaques, 0.5 cm × 0.5 cm ~ 3.0 cm × 2.5 cm , The surface is dry, part of the skin lesions attached to the thick crusts and scales, clear boundaries, the right wrist rash surface scab off, slightly erosion of the base, exudation, mucosal sites were not involved. Histopathological examination of skin lesions: irregular hyperplasia of the epidermis, disordered cells, atypical hyperplasia, poor keratinocytes and pathological mitosis. Diagnosis: Multiple Bowen’s disease.