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A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines.
A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-aryl propionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines.