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丹参水提取物(SM-H)预防异丙肾上腺素(ISO)或氯化钡引起大白鼠急性心肌缺血和心律失常有如下的显著效应:(1)腹腔注射 SM-H,连续3～5天,或1次静脉注射,均能显著地减少动物的死亡率;(2)静脉注射 SM-H 进行氯化钡恒速灌注,显著提高导致动物心律失常而致死的氯化钡剂量;(3)腹腔注射 SM-H,显著防止或减少氯化钡静脉注射引起大白鼠的室性过早搏动、心室纤颤、心搏过缓以及死亡率;(4)腹腔注射 SM-H,能显著缩小 ISO 引起大白鼠心电图的 J-点位移。
The effects of SM-H on the prevention of acute myocardial ischemia and arrhythmia in rats induced by isoproterenol (ISO) or strontium chloride have the following significant effects: (1) Intraperitoneal injection of SM-H, 3 to 5 consecutive times Day or one intravenous injection can significantly reduce the mortality rate of the animal; (2) Intravenous injection of SM-H at a constant rate of perfusion of cesium chloride significantly increases the dose of strontium chloride that causes death due to arrhythmia in the animal; (3 ) Intraperitoneal injection of SM-H significantly prevented or reduced ventricular premature beats, ventricular fibrillation, bradycardia, and mortality caused by cesium chloride intravenous injection; (4) Intraperitoneal injection of SM-H, can significantly reduce ISO causes J-point displacement of the electrocardiogram in rats.