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采用垂体后叶素诱发Ｗｉｓｔａｒ大鼠心肌缺血模型，观察补阳还五汤对其保护作用。结果表明补阳还五汤可显著抑制大鼠Ｔ波变化，提高大鼠血浆ＳＯＤ活性、降低ＭＤＡ含量，对血素ＬＤＨ、ＣＰＫ的释放也有显著的抑制作用。提示本方对心肌缺血损伤的保护作用可能与其减轻氧自由基对心肌膜脂质过氧化损伤反应有关
The model of myocardial ischemia induced by pituitrin in Wistar rats was used to observe the protective effect of Buyang Huanwu Decoction. The results showed that Buyang Huanwu Decoction can significantly inhibit the T wave changes in rats, increase plasma SOD activity, reduce MDA content, and also have a significant inhibitory effect on the release of blood LDH, CPK. It is suggested that the protective effect of this prescription on myocardial ischemic injury may be related to the reduction of oxygen free radicals on myocardial lipid peroxidation