本文报告13例软骨母细胞瘤,年龄12～33岁,平均21.8岁,男7例,女6例。手术前全部误诊,误诊为骨巨细胞瘤10例,骨肉瘤2例和内生软骨瘤1例。手术后病理误诊3例,经再次手术活检方确定。12例病灶刮除加植骨,随访3年～21年,10例未复发,1例复发,1例复发并2次发生肺部转移,1例截肢后17年无异常发现。对本病的诊断和治疗进行了讨论。 This article reports 13 cases of chondroblastoma, aged 12 to 33 years, an average of 21.8 years old, 7 males and 6 females. All misdiagnosed before surgery, misdiagnosed as bone giant cell tumor in 10 cases, 2 cases of osteosarcoma and endochondroma in 1 case. Three cases were misdiagnosed after surgery and were confirmed by reoperation biopsy. Twelve lesions were scraped and bone grafted. During 3 to 21 years of follow-up, 10 patients had no recurrence, 1 had recurrence, 1 had recurrence and 2 had lung metastasis, and 1 had no abnormal findings 17 years after amputation. The diagnosis and treatment of the disease were discussed.