在Ⅰ型多发性内分泌腺瘤病(MEA)中胰岛素分泌过多,是由多发性良性胰岛素瘤或弥漫性微腺瘤病造成的,所以其治疗方案与单个胰岛素瘤病截然不同。一名15岁女孩,有Ⅰ型 MEA 家族史,表现为可逆性精神病学障碍,低血糖和高胰岛素血症。门静脉抽样分析提示胰尾部有一胰岛素瘤,切 Insulin hypersecretion in type I multiple endocrine neoplasia (MEA) is caused by multiple benign insulinomas or diffuse microadenomatous disease, so its treatment regimen is distinctly different from single insulinomatosis. A 15-year-old girl with a family history of type I MEA showed reversible psychiatric disorders, hypoglycemia, and hyperinsulinemia. Portal sampling analysis suggests that there is an insulinoma in the tail of the pancreas.