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近年来,国内外应用具有较强穿透力的Co~(60)作为辐照能源,对药物及其制剂进行常温辐射灭菌研究已有较多报道,文献指出有些药物制剂经用能祛除热原的一定辐射剂量灭菌后,其药物的结构及理化性质仍能保持不变。生理盐水制剂经辐照10×10~6rad(拉德)剂量后,不仅可符合热原要求,其理化性质仍能保持稳定。但以这种方法灭菌后的注射剂
In recent years, the application of Co ~ (60) with high penetrating power at home and abroad as the irradiation energy has been reported in the field of radiation sterilization of drugs and their preparations at room temperature. The literature points out that some pharmaceutical preparations can be used to eliminate heat The original radiation dose sterilization, the drug’s structure and physical and chemical properties can be maintained. After the dosage of 10 × 10 ~ 6 rad (Rad) dose of saline solution can not only meet the requirements of pyrogen, its physical and chemical properties can still be kept stable. However, injectables sterilized in this way