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因为白细胞介素2受体新的表达是T细胞活化的必需步骤,故迟发型超敏反应(DTH)需要抗原特异性辅助T细胞(Th)的刺激。本文作者曾研究抗鼠IL-2R单克隆抗体(McAb)和抗鼠Th(抗L_3T_4)McAb阻止DTH的能力。著者检测了上述抗体对两个不同DTH系统的
Because new expression of interleukin 2 receptor is an essential step in T cell activation, delayed-type hypersensitivity (DTH) requires stimulation of antigen-specific helper T cells (Th). The authors studied the ability of anti-mouse IL-2R monoclonal antibodies (McAbs) and anti-mouse Th (anti-L_3T_4) McAbs to block DTH. The authors tested the above antibodies against two different DTH systems