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自1933年Soder报告了第一例发生在中耳的横纹肌肉瘤以来,有关于本病的文献即络续报导,Stobbe和Dargeon在1950年曾一次报告15例头颈部患者,其中有2例发生在中耳和乳突。截至1978年前后关于本病有文献记述的累计数字为:鼻咽部96例,喉部9例,中耳和乳突88例,鼻窦11例。【发病情况】横纹肌肉瘤多见于儿童,占儿童恶性肿瘤总数的4～8%,美国15岁以下儿童年发病率为百万分之5.7。美国横纹肌肉瘤协作研究组分析了554例横纹肌肉瘤,最常发生的部位为头颈部,占38%;其次是泌尿生殖道,21%;四肢18%,躯干和腹膜后各7%,其他部位9%。【病理形态学】横纹肌肉瘤在大体形态上无
Since Soder reported the first case of rhabdomyosarcoma in the middle ear in 1933, there was a continuous report on the disease. Stobbe and Dargeon had reported 15 cases of head and neck patients in 1950, including 2 cases. In the middle ear and mastoid. As of 1978, there were cumulative numbers of articles describing the disease: 96 cases of nasopharynx, 9 cases of larynx, 88 cases of middle ear and mastoid, and 11 cases of paranasal sinus. The incidence of rhabdomyosarcoma is more common in children, accounting for 4 to 8% of the total malignancy of children, and the annual incidence of children under 15 years of age in the United States is 5.7 parts per million. The United States Rhabdomyosarcoma Collaborative Study Group analyzed 554 cases of rhabdomyosarcoma, the most common site was the head and neck, accounting for 38%; followed by the urogenital tract, 21%; limbs 18%, the trunk and retroperitoneal 7%, other parts 9%. Pathological morphology Rhabdomyosarcoma has no gross morphology