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近两年来大量研究报道了新近发现的Th17细胞在抗微生物免疫和自身免疫性疾病的小鼠模型中发挥的重要作用。对于类风湿性关节炎、系统性红斑狼疮、多发性硬化等疾病活性期的患者的血液和组织细胞的研究也发现,在人类同样存在着分泌IL-17为主的CD4+T细胞,并提示提示人类的Th17在
Numerous studies in recent years have reported the important role of the newly discovered Th17 cells in a mouse model of antimicrobial and autoimmune diseases. Studies on blood and tissue cells in patients with active phases of rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and the like also show that IL-17-dominant CD4 + T cells also exist in humans and suggest Prompt human Th17 in