论文部分内容阅读
Ag—NOR技术是近几年来在国外受到广泛重视应用于肿瘤病理学研究的一项新指标。这一技术首先被细胞遗传学家应用于某些染色体疾病的研究,如21—三体综合征等。直到1986年ploton等改良Ag—NOR的染色方法,并发现前列腺癌细胞与良性增生细胞银染颗粒数量和分布有显著差异。自从这一发现以来,已有不少学者把这一方法应用于肿瘤的研究,并认为它对一些肿瘤鉴别诊断,区分良恶性病变及肿瘤分型,分级具有一定价值。本文用Ag—NOR染色技术,对我院近2年62例结肠肿瘤进行了Ag—NOR定量研究,以观察这一方法在结肠肿瘤研究及鉴别诊断中的应用价值。
Ag-NOR technology is a new indicator that has been widely used abroad for tumor pathology research in recent years. This technique was first applied by cytogeneticists to the study of certain chromosomal diseases such as 21 trisomy syndrome. Until 1986, Ploton et al. improved the Ag-NOR staining method and found significant differences in the number and distribution of silver-stained particles between prostate cancer cells and benign hyperplastic cells. Since this discovery, many scholars have applied this method to the study of tumors, and believe that it has certain value for the differential diagnosis of some tumors and the differentiation of benign and malignant lesions and tumor types. In this paper, Ag-NOR staining technique was used to quantitatively study Ag-NOR in 62 cases of colon cancer in our hospital in the past 2 years to observe the value of this method in the study and differential diagnosis of colon cancer.