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用RIA法检测111例原发性肝癌(PHC)(AFP>20ng/L86例、AFP≤20ng/L25例),342例急慢性肝炎及58例其它恶性肿瘤共计511例患者血清铁蛋白(SF),并与102例健康人群对照,结果显示:PHC组SF水平明显高于其它恶性肿瘤(P<0.001)和各种肝炎(P<0.05),尤其是血清SF检测对AFP≤20ng/L的25例PHC诊断敏感性高达92%,且10例PHC手术前后SF对比有显著差异(P<0.001)。故认为SF测定可能对早期诊断PHC,尤其AFP含量低的PHC是一个比较灵敏的指标。
Serum ferritin (SF) was detected in 511 patients with primary hepatocellular carcinoma (PHC) (AFP> 20ng / L, AFP≤20ng / L25), 342 patients with acute and chronic hepatitis and 58 other malignancies with RIA. , And compared with 102 healthy people. The results showed that SF level in PHC group was significantly higher than that in other malignant tumors (P <0.001) and various hepatitis (P <0.05), especially for serum SF in AFP≤20 ng / L 25 Cases of PHC diagnostic sensitivity as high as 92%, and 10 cases of PHC before and after surgery SF significant difference (P <0.001). Therefore, the determination of SF may be early diagnosis of PHC, especially low PHC PHC is a more sensitive indicator.