目前,肺内分泌细胞与疾病的关系越来越受到人们的重视。本文简介正常肺内分泌细胞和支气管炎与肺气肿患者的肺内分泌细胞改变。 Cutz E等曾应用PAP法对正常肺内分泌细胞进行了研究。他们发现肺内分泌细胞中,无论是孤立细胞还是神经上皮小体(N-EBs),均含有5-羟色胺、蛙皮素和降钙素;仅孤立细胞含亮氨酸—脑啡肽。各年龄组中均测出蛙皮素、降钙素和亮氨酸—脑啡肽。含蛙皮素的细胞数目最多,含降钙素的细胞较少,含亮氨酸—脑啡肽的细胞极少。含蛙皮素的细胞散在分布于气道上皮,胎儿肺中见于各级支气管树,而在生后及成人肺组织 At present, the relationship between pulmonary endocrine cells and diseases has drawn more and more attention. This article describes the normal pulmonary endocrine cells and bronchitis and emphysema in patients with lung endocrine cells. Cutz E et al. Used PAP to study normal pulmonary endocrine cells. They found that all lung endocrine cells, whether isolated or neuroepithelial bodies (N-EBs), contained serotonin, bombesin and calcitonin; only isolated cells contained leucine-enkephalin. Bombesin, calcitonin and leucine-enkephalin were measured in all age groups. The number of cells containing bombesin the most, less calcitonin-containing cells, leucine-enkephalin-containing cells rarely. Bone cells containing bombesin scattered in the airway epithelium, fetal lungs found in all levels of bronchial tree, and in postnatal and adult lung tissue