鱼类肠炎病是导致水产养殖经济损失的主要疾病之一。在鱼药市场上,用于防治肠炎病的药物种类很多,在禁止使用呋喃类、磺胺类中某些药物之后,许多厂家转向生产一些以磺胺类、喹诺酮类、土霉素类等抗生素为原料的药物,大量、长期地使用这些药物,极容易产生耐药菌株,导致局部地区鱼类肠炎病频频暴发,出现用药量加大和久治不愈等现象。药量加大及药残也造成水产动物潜在性地危害人体健康。因 Fish enteritis is one of the major causes of the economic loss of aquaculture. In the fish medicine market, there are many kinds of drugs used to prevent and control enteritis. After some drugs such as furans and sulfonamides are forbidden, many manufacturers turned to some antibiotics such as sulfonamides, quinolones and oxytetracyclines Of the drug, a large number, long-term use of these drugs, extremely resistant strains, leading to frequent outbreaks of fish enteritis in some areas, the emergence of increased dosage and prolonged treatment and so on. Dosage and drug residues also cause aquatic animals potentially harmful to human health. because