,aPKC ι/λ: a potential target for the therapy of Hh-dependent and Smo-inhibitor-resistant advanced B

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Basal cell carcinoma (BCC),a skin cancer,is the most common malignancy in white people [1,2].Although mortality is low as BCC rarely metastasizes,people suffering from BCC are at high risk of developing other malignancies [3].Given its low metastatic potential,treatment of BCC focuses on local control,including surgical and non-surgical measures [3,4].In the best hands,the 5-year cure rates of excision,curettage and cautery,and cryosurgery are 95% or higher [3].
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