论文部分内容阅读
目的:通过观察急性脑梗死患者发病前的血压及用药情况,探讨患者在预防急性脑梗死发生时较好血压范围。方法:观察组48例,男28例,女20例,年龄54岁~81岁,平均年龄(66.51±12.54)岁,病程4.2a~12.5a,平均病程(7.91±4.24)a;对照组52例,男33例,女19例,年龄49岁~82岁,平均年龄(64.52±15.70)岁,病程3.8a~12.9a,平均病程(8.11±4.04)a。两组基础治疗为口服北京降压0号,1片/d,部分患者治疗加服了倍他乐克25mg/d或卡托普利25mg/d,疗程均超过2a。结果:二组在发病时血压不同,观察组(108±6)/(65±6)mmHg,对照组(118±7)/(70±5)mmHg,两组的收缩压差异有显著性(P<0.05),发病率分别为66.67%和40.38%,差异有显著性(P<0.05)。结论:高血压治疗的同时应注意收缩压的变化调整用药,避免因收缩压的降低造成脑灌注压的不足,从而诱发脑梗死的发生。
Objective: To observe the blood pressure and medication before onset of acute cerebral infarction patients to explore the patients in the prevention of acute cerebral infarction better blood pressure range. Methods: The observation group of 48 cases, 28 males and 20 females, aged 54 years to 81 years, mean age (66.51 ± 12.54) years, duration of 4.2a ~ 12.5a, the average duration (7.91 ± 4.24) a; control group 52 Cases, 33 males and 19 females, aged 49 years to 82 years, mean age (64.52 ± 15.70) years, duration of 3.8a ~ 12.9a, the average duration (8.11 ± 4.04) a. The two groups of basic treatment for oral Beijing blood pressure 0, 1 / d, some patients treated with metoprolol 25mg / d or captopril 25mg / d, treatment were more than 2a. Results: There were significant differences in systolic blood pressure between the two groups (108 ± 6/65 ± 6 mmHg vs 118 ± 7/70 ± 5 mmHg in the observation group P <0.05), the incidence rates were 66.67% and 40.38% respectively, with significant difference (P <0.05). Conclusion: Hypertension treatment should pay attention to changes in systolic blood pressure to adjust medication, to avoid reduced systolic blood pressure caused by inadequate cerebral perfusion, thereby inducing cerebral infarction.