患者,女,27岁,诊断为心因性扰郁,心电图检查窦性心律不齐。给予丙咪嗪治疗,开始剂量每次50mg,一日2次,次日改为每次75mg,每日两次,第13天改为每次100mg,每日两次。用药后3～4天病情开始好转,自觉心情开朗。服药第16天,出现脉搏缓慢,心率52次/分,患者感觉胸闷,心电图示窦性心动过缓、房性早搏来下传呈二联律。诊断为丙咪嗪对心脏的毒性反应,减少剂量为每次50mg,每日两次,次日停用,给B族维生素、阿托品及中药参味合 Patient, female, 27 years old, diagnosed as having a cardiac disorder, electrocardiographic examination of sinus arrhythmia. Give imipramine treatment, the initial dose of 50mg, 2 times a day, the next day changed to 75mg twice daily, the first 13 days to 100mg twice a day. 3 to 4 days after treatment began to improve, consciously cheerful. Medication on the 16th day, there pulse slow, heart rate 52 beats / min, the patient feels chest tightness, ECG shows sinus bradycardia, atrial premature beats to the next couplet law. Diagnosis of imipramine on the heart of the toxic reaction to reduce the dose of 50mg twice daily, disabled the next day, to B vitamins, atropine and Chinese herbal medicine ginseng