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Ob基因是脂肪细胞特异性基因 ,其编码产物称为瘦素 ,瘦素近年来被认为是由脂肪细胞分泌的一种激素 [1～ 3 ] ,其血清浓度的高低与体内脂肪的百分比有关。但其在人体中诸多生理作用还不被人们所了解 ,原发性甲状腺机能减退 (简称甲减 )及原发性甲状腺机能亢进 (简称甲亢 )中血清
Ob gene is a fat cell-specific gene whose coding product is called leptin. Leptin has been considered as a hormone secreted by adipocytes in recent years [1 ~ 3]. The serum level of leptin is related to the percentage of body fat. However, its physiological role in the human body is not yet understood, the primary hypothyroidism (referred to as hypothyroidism) and primary hyperthyroidism (hyperthyroidism) serum