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肝硬化、肝癌与HBV癌染有密切关系,而乙肝病毒HBV DNA是判断HBV感染、复制状态、传染性及考核抗病毒疗效的一个重要标志。随着分子生物学研究技术的迅速发展,新建立聚合酶链反应(PCR)检查HBV DNA,有较高的特异性与灵敏性。本文应用该法检测HBsAg阴性肝硬化、肝癌患者血清中HBV感染情况,结果报告如下。
Cirrhosis, liver cancer and HBV cancer are closely related, and hepatitis B virus HBV DNA is to determine HBV infection, replication status, infectious and antiviral effect of an important sign. With the rapid development of molecular biological research techniques, a new polymerase chain reaction (PCR) to detect HBV DNA has high specificity and sensitivity. The application of this method to detect HBsAg-negative cirrhosis, serum HBV infection in patients with liver cancer, the results reported below.