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报道温州地区胃癌高发区瑞安塘下的致癌危险因素的调查情况,结果表明它是由多种致癌危险因素的综合影响。作者应用内镜活检在18000例慢性胃病患者中查出癌前病变(高危人群)1132例,经3月～14年活检随访,表明胃癌前病变有一定的可逆转性;癌变率较高的是胃溃疡(GU)+不典型增生(ATP)组、GU+慢性萎缩性胃炎(CAG)组及CAG+ATP组均为4.1％;总癌变率为3.1％。早癌检出率占胃癌总数的48.6％,为门诊早癌检出率的6.8倍。此方法简单、经济实用。
The investigation of the risk factors for carcinogenicity in Ruiantangxia, a high-risk area of gastric cancer in Wenzhou, was reported. The results showed that it was caused by a combination of multiple carcinogenic risk factors. The authors applied endoscopic biopsy to detect 1132 cases of precancerous lesions (high-risk groups) among 18,000 patients with chronic gastritis. Follow-up biopsy from March to 14 showed that the precancerous lesions of gastric cancer were reversible; the rate of canceration was high. Gastric ulcer (GU) + atypical hyperplasia (ATP) group, GU + chronic atrophic gastritis (CAG) group and CAG + ATP group were 4.1%; total cancer rate was 3.1%. The detection rate of early cancer accounts for 48.6% of the total number of gastric cancers, which is 6.8 times the detection rate of outpatients with early cancer. This method is simple, economical and practical.