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目的总结我院治疗胃平滑肌肉瘤 (GLS)的临床经验 ,以提高对本病的认识和疗效 .方法回顾性分析本院 33年来收治的 GLS 21例的临床资料 ,生存过程描述采用 Kaplan- Meier生存曲线法 .结果本组 GLS以上腹胀痛不适、上消化道出血及腹部肿块为主要临床表现 ,其中以上消化道出血尤为突出 .本组肿瘤全切除的 12例患者 5年、 10年生存率为 67%和 50% ,肿瘤不全切除的 8例患者仅 2例生存了 5年 , 10年生存率为 0,本组总的 5年、 10年生存率为 47%和 37% .结论 GLS是胃部常见非上皮性恶性肿瘤 ,但临床极易误诊 ,故应提高警惕 ,综合分析 ,才能提高本病的诊断率 .为了提高生存率和生存质量 ,对原发肿瘤主张肿瘤全切除 ,对术后的复发灶和转移灶 ,主张积极的再切除 ,但不主张行扩大的淋巴结清除术 .
Objective To summarize the clinical experience of treatment of gastric leiomyosarcoma (GLS) in our hospital to improve the knowledge and efficacy of the disease. Methods Retrospective analysis of the clinical data of 21 cases of GLS treated in our hospital for 33 years, the survival process described using Kaplan-Meier survival Curve method. The results of the above group of GLS abdominal pain and discomfort, upper gastrointestinal bleeding and abdominal mass as the main clinical manifestations, especially the more prominent gastrointestinal bleeding. The total tumor resection in 12 patients with 5-year, 10-year survival rate of 67 In 5 and 80% of 8 patients with incomplete tumor resection, only 2 patients survived for 5 years and the 10-year survival rate was 0. The total 5-year and 10-year survival rates in this group were 47% and 37%. Conclusions GLS is the stomach Common non-epithelial malignancies, but clinically misdiagnosed, it should be vigilant, comprehensive analysis, in order to improve the diagnostic rate of this disease. In order to improve the survival rate and quality of life, the primary tumor for total tumor resection, after surgery Recurrent foci and metastases, advocate positive re-excision, but do not advocate the expansion of lymph node dissection.