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睾丸素是临床上一种重要的雄性激素,它在胃肠吸收非常差,已经证明睾丸素不宜用于口服治疗。Estwood提出,睾丸素很快被吸收,然而这种吸收完全无效,因为这种激素在进入全身循环以前在肝中已经改变。
Testosterone is an clinically important androgenic hormone that is very poorly absorbed in the gastrointestinal tract and has been shown not to be useful in oral therapy. Estwood suggests that testosterone is rapidly absorbed, however this absorption is completely ineffective because the hormone has changed in the liver before it enters systemic circulation.