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急性冠状动脉阻塞的临床实验和观察提示,晚期再灌注能防止梗塞扩展(infarct ex-pansion)并有助于心肌痊愈。本文评价在晚期入院的急性心肌梗塞(AMI)病人是否能使梗壁区供血冠脉开放,并试图证明其好处。对象和方法以症状出现6～24小时和心电图有2个或2个以上导联ST段抬高≥1mm的197例AMI病人作为对象,排除:(1)年龄>75岁,(2)胸痛可被硝酸甘油缓解,(3)有卒中或新近手术或外伤史,(4)有出血倾向,(5)在梗塞区供血冠状动脉分布范围内以前有Q波梗塞,(6)血压>24.0/14.7kPa(180/110mmHg)等。
Clinical trials and observations of acute coronary occlusion suggest that late reperfusion prevents infarct ex-pansion and contributes to cardiac recovery. This article assesses whether AMI patients admitted to the late stage of hospital can open coronary arteries in the infarct wall and attempt to demonstrate their benefits. Subjects and Methods Ninety-seven AMI patients with symptoms of 6-24 hours and 2 or more ST-segment elevation ≥1 mm in the ECG were excluded from the study. Subjects were: (1)> 75 years of age, (2) chest pain Is relieved by nitroglycerin, (3) has a history of stroke or recent surgery or trauma, (4) has a tendency to hemorrhage, (5) has previous Q wave infarction within the distribution of coronary arteries in the infarct area, (6) has a blood pressure> 24.0 / 14.7 kPa (180 / 110mmHg) and so on.