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复方醋酸钠注射液和口服补液散中分别含有醋酸钠和碳酸氢钠,由于它们的水溶液碱性较弱及其它共存组分的干扰,直接酸碱滴定时终点不明显。本文采用交流示波极谱滴定、非水滴定和在浓盐溶液中酸碱滴定等法进行测定和比较。一、交流示波极谱中和滴定法 (一)实验条件的选择 1.指示剂的选择:醋酸钠和碳酸氢钠用盐酸滴定,终点的pH值分别为3.50和4.10左右,分别选用0.1％甲基红和0.1％溴甲酚绿为指示剂。试验了不同用量指示剂切口变化的pH值情况,甲基红指示剂与溴甲酚绿指示剂的用量分别为0.60～1.00和0.30～0.50ml(均加KCl1g)。
Sodium acetate and sodium bicarbonate are contained in the compound sodium acetate injection and oral rehydration powder, respectively. Due to the weak basicity of their aqueous solution and the interference of other co-existing components, the end point of the direct acid-base titration is not obvious. In this paper, AC oscillopolarographic titration, non-aqueous titration and acid-base titration in concentrated salt solution were measured and compared. First, the exchange of oscillopolarography and titration (a) the choice of experimental conditions 1 indicator selection: sodium acetate and sodium bicarbonate titration with hydrochloric acid, the end point of the pH values were 3.50 and 4.10 or so, were selected 0.1% Methyl red and 0.1% bromocresol green as an indicator. The pH value of different dosage indicator slits was tested. The dosage of methyl red indicator and bromocresol green indicator were 0.60-1.00 and 0.30-0.50ml (both plus KCl1g).