脑动脉粥样硬化是缺血性脑血管的主要病理基础,其发生与遗传因素和生活方式影响的诸多危险因素密切相关。近年来虽在脑动脉粥样硬化的发病机制研究方面取得很大进展,但确切机制仍未完全阐明。由于人体研究受到诸多条件的限制,所以建立动物模型成为研究的主要途径。然而,国内外 Cerebral atherosclerosis is the main pathological basis of ischemic cerebrovascular disease, its occurrence and genetic factors and lifestyle factors are closely related to many risk factors. Although great progress has been made in the study of the pathogenesis of cerebral atherosclerosis in recent years, the exact mechanism has not yet been fully elucidated. Since human studies are limited by many conditions, the establishment of animal models has become the main method of research. However, at home and abroad