强啡肽(Dynorphin,Dyn)是不同于脑啡肽或β—内啡肽的一族内阿片肽,其结构、分布及作用受体,笔者曾有过叙述,现专就强啡肽的功能综述如下: 一、对某些中枢核团电活动及递质释放的影响 Walker等看到,局部电泳Dyn可抑制海马单位活动,纳洛酮不影响此效应。但也有人报告Dyn抑制海马神经元放电的效应可被纳洛酮阻断。Gruol等则在海马 Dynorphin (Dyn) is a family of endo-opioid peptide which is different from enkephalin or β-endorphin. Its structure, distribution and receptors are described by the author. As follows: First, the impact of some of the central nucleus electrical activity and neurotransmitter release Walker and other see, local electrophoresis Dyn can inhibit hippocampal unit activity, naloxone does not affect this effect. However, it has also been reported that the effect of Dyn on hippocampal neuronal firing can be blocked by naloxone. Gruol and so on in the hippocampus