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Leser—Trelat征(L—T征),是急性发疹性脂溢性角化病,有可能是内脏恶性肿瘤在皮肤上的反映。最近我们观察1例本病合并食管癌患者,皮肤损害病理组织象较特殊,因较罕见,报告于下。患者袁某某,男,76岁,汉族,河南籍。门诊号26037。1983年5月以左颈部包块渐大6个月主诉就诊。始于左颈部皮下出现硬结,渐增多、长大、互相融合粘连,无不适感,亦无其他头面五官及内脏各系统症状。36年前(40岁)开始在胸背皮肤出现少数淡褐色小斑,缓慢地变大增多,高起,色素加深。皮疹逐渐蔓延至头颈及上肢。无自觉症。近四年来,褐色斑更加增多并很快延及全身。皮损与季节及日晒无关。家族中有7人(三代)发生同样皮损(图1)家族癌症史不明。
The Leser-Trelat sign (L-T sign) is an acute eruptive seborrheic keratosis that may be a reflection of visceral malignancy on the skin. Recently, we observed one case of esophageal cancer patients with this disease, skin lesions like special pathological tissue, as relatively rare, reported in the next. The patient Yuan Moumou, male, 76 years old, Han nationality, Henan origin. Outpatient No. 26037. In May 1983, the patient complained of a gradual increase in left neck mass for 6 months. The induration began at the subcutaneous neck of the left neck and gradually increased, grew up, and merged and adhered to each other without any discomfort. There were no other facial or facial symptoms. 36 years ago (40 years old) began to appear in the thoracodorsal skin, a small number of light brown spots, slowly increased larger, higher, deeper pigment. The rash gradually spread to the head and neck and upper extremities. No consciousness. In the past four years, brown spots have increased and spread rapidly throughout the body. Lesions have nothing to do with the season and the sun. Seven people (three generations) in the family had the same lesion (Figure 1). The family history of cancer was unknown.