血小板是止血和血栓形成的主要成分之一。近年发现,血小板所释放的糖蛋白(如TSP、FN,vWF)及其他成分(如血小板纤溶增强物、PAF、AA及PGs)可与纤溶系统相互作用,并通过促进或抑制血纤维蛋白溶酶原的活化而影响纤溶系统的活性。因此,阐明血小板与纤溶系统的作用机制,对于临床及基础研究均具有重要的实践意义。 Platelets are one of the major components of hemostasis and thrombosis. In recent years, glycoproteins (such as TSP, FN, vWF) and other components released by platelets (such as platelet fibrinolysis enhancers, PAF, AA and PGs) have been found to interact with the fibrinolytic system and by promoting or inhibiting fibrin Activation of plasminogen affects the activity of the fibrinolytic system. Therefore, elucidating the mechanism of action of platelets and fibrinolytic system has important practical significance for both clinical and basic research.