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海参(sea cucumber,Ludwigothurea grisea)属棘皮动物门、海参纲、盾手目动物。全世界可食用海参40多种,我国有20多种。海参作为一种海洋药物,对当前威胁人类健康的几大疾病均有一定的疗效,如:癌症、心血管疾病、病毒性肝炎、艾滋病、免疫疾病及老年病等。世界上最早的海参药用记载出自《本草纲目拾遗》:刺参有治出血性疾病的实例。中医认为:“其性温补,足敌人参,故曰海参”。现代药理研究表明,海参具有多种药理活性,包括抗氧化、延缓衰老、抗凝血、抗血栓、降血脂、降低血粘度、抗肿瘤、免疫调节、抗菌、抗病毒及促细胞生长等作用。随着研究的广泛和深入,关于海参治疗糖尿病的作用逐渐成为大家关注的热点,我们就近几年海参治疗糖尿病方面的动物研究进展做一简要综述。
Sea cucumber (sea cucumber, Ludwigothurea grisea) is an echinoderm, sea cucumber class, shield hand animal. Over 40 kinds of edible sea cucumbers in the world and more than 20 kinds in our country. As an ocean medicine, sea cucumber has some curative effects on several major diseases that threaten human health, such as cancer, cardiovascular diseases, viral hepatitis, AIDS, immune diseases and geriatric diseases. The world’s earliest medicinal records of sea cucumber from the “Compendium of Materia Medica”: Acupuncture have governance hemorrhagic disease example. Chinese medicine believes that: “its sexual warm up, enough enemy ginseng, it is said sea cucumber ”. Modern pharmacological studies have shown that sea cucumber has a variety of pharmacological activities, including anti-oxidation, anti-aging, anticoagulant, antithrombotic, hypolipidemic, lower blood viscosity, anti-tumor, immune regulation, antibacterial, antiviral and cell growth and so on. With the extensive and in-depth research, the role of sea cucumber in the treatment of diabetes has gradually become the focus of attention, we have made a brief review of animal research progress in the treatment of diabetes with sea cucumber in recent years.